Protein Details: Gap junction alpha-3 protein

Protein ID

ICDB_Pro_1648

Protein Name

Gap junction alpha-3 protein

Gene Name

GJA3

Organism

Ovis aries (Sheep)

Length

413 amino acids

AlphaFoldDB

AF-Q9TU17-F1-model_v4.pdb

Function

Sequence

MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEEVWGDEQSDFTCNTQQPGCENVCYDRAFPISHVRFWVLQIIFVSTPTLIYLGHVLHLVRMEEKRKEREEEPPKAAGPAEEHQDPAPVRDDRGKVRIAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFQLKPLYRCDRWPCPNTVDCFISRPTEKTIFILFMLAVACVSLLLNVLEIYHLGWKKLKQGMTSPFRPDTPGSRAGSAKPMGGSPLLLPPNSAPPAVTIGFPPYYAPSASSLGQASAPGYPEPPLPAALPGTPGTPGTPGTLGGGGGNQGLRAPAQNCANREAEPQTSARKASPPASTPPAAPAGGPQQFLPGGAAGSSGDSDGEGAVTAVELHAPPEPPADPGRSSKASKSSGGRARAADLAI

PDB Structures

6MHQ 7JKC 7JMD 7JN0 7JN1

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

Detected in eye lens (at protein level) (PubMed:30542154). Only detected in the lens. Not detected in heart; kidney; liver; or lung. Not detected in heart; kidney; liver; or lung. Not detected in heart; kidney; liver; or lung.

DOI ID

10.1038/s41586-018-0786-7